To wait or delay.
Hold up a minute. I want to check something.
To impede; detain.
I've got to be to work now. Why are you holding me up?
To support or lift.
Hold up the table while I slide this underneath.
To withstand; to stand up to; to survive.
hold up to heavy use
To fulfil or complete one's part of an agreement.
To rob at gunpoint.
The guy tried to hold up a bank.
To keep up; not to fall behind; not to lose ground.